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Cognitive / Nootropic Developed in Russia and studied there for anxiety-related conditions; not approved for human use in Australia. Evidence outside small regional studies is limited.

Selank

Also known as: TP-7

Selank is a synthetic peptide developed in Russia, based on the immunomodulatory peptide tuftsin. It is studied chiefly for reported anti-anxiety and cognitive effects and is not approved for human use in Australia.

Category
Cognitive / Nootropic
Reported half-life
Not well established
Common forms
Lyophilised powder for reconstitution, Nasal spray (research preparations)
Research status
Developed in Russia and studied there for anxiety-related conditions; not approved for human use in Australia. Evidence outside small regional studies is limited.
Last updated
21 June 2026

Claimed effects

The following effects are reported or claimed by users and in early research. They are not established medical facts and many are not supported by large human trials.

  • Reported to have anti-anxiety (anxiolytic) effects in early research
  • Reported to influence mood and stress resilience
  • Studied for possible effects on attention and memory
  • Reported to interact with the immune and BDNF/enkephalin systems

How it is reported to work

Selank is proposed to act as a synthetic analogue of the endogenous peptide tuftsin, with reported effects on the balance of monoamines, expression of brain-derived neurotrophic factor (BDNF), and modulation of enkephalin breakdown. These proposed mechanisms come largely from animal and small Russian human studies and should be regarded as preliminary rather than established.

Background

Selank is a synthetic peptide derived from tuftsin, a naturally occurring immune-related peptide. It was developed in Russia, where it has been studied as a potential anti-anxiety agent. This page is educational information, not medical advice, and the effects described below are reported claims, not established facts.

What the research shows

Most published research on Selank consists of animal studies and small human trials conducted in Russia. These suggest possible anxiolytic and cognitive effects, but the body of evidence is limited and has not been replicated in large international trials.

Evidence typeStatus
Animal studiesPresent
Small regional human studiesSome
Large international trialsLacking
Australian approvalNone

What people use it for (reported)

Online, people report interest in Selank for stress, mood and focus. These are anecdotal reports, not validated clinical outcomes. Reported benefits should not be read as proven, and nothing here should be taken as encouragement to use it.

Things to be aware of

Selank is not approved for human use in Australia. Its long-term safety profile in humans is not well understood, and grey-market preparations cannot be verified for purity or identity by sight. If you have anxiety or other health concerns, the appropriate step is to speak with a qualified healthcare professional. This article does not recommend obtaining or using Selank.

Reported positives & side effects

Compiled from research and community reports. These are reported outcomes, not guarantees or medical advice, individual experiences vary widely.

Reported positives

  • Reported reduction in anxiety and a calmer feeling
  • Reported improvement in stress resilience
  • Reported subtle support for focus and mental clarity
  • Reported mood stabilisation in early research
  • Reported as non-sedating compared with some anxiolytics

Common side effects

  • Nasal irritation or congestion reported with the nasal-spray form
  • Drowsiness or fatigue reported by some users
  • Headache reported
  • Altered sense of smell or taste reported transiently

Rare / serious side effects

  • Allergic or hypersensitivity reactions reported
  • Unexpected mood changes reported by some users
  • Unknown long-term effects from unverified grey-market product

Reported misuse & overdose risks

What has been reported to happen with overuse, excessive dosing, or long-term misuse of Selank. Listed so you can make an informed decision, not to suggest any use is safe.

  • Reported daily dosing far above amounts used in Russian studies seeking stronger effects
  • Reported use of unverified grey-market product with uncertain identity and purity
  • Reported self-treatment of clinical anxiety in place of professional care
  • Reported stacking with multiple nootropic peptides without monitoring

Reported results timeline

Roughly how long people report it takes to notice effects. A general guide from reports, not a promise, and not advice. Calming effects are reported as fast, often the same day, with mood and anxiety benefits reported building over one to three weeks.

  1. First effects

    Reported calming effect within hours of the same day

  2. Noticeable change

    Reported steadier mood and reduced anxiety over days

  3. Clear results

    Reported cumulative anxiolytic and focus benefits

Commonly reported dosing & protocol

Reported figures only, NOT a recommendation or dosing advice. These are numbers people report using, compiled for education so you can make an informed decision. We do not advise anyone to take Selank. Many peptides are not approved for human use in Australia. Speak to a qualified healthcare professional.

Commonly reported dosing for Selank
RouteIntranasal (also reported subcutaneously)
Typical reported doseReported as roughly 250-300 mcg per intranasal dose per day; subcutaneous use is reported at roughly 250-500 mcg
FrequencyReported as once daily, sometimes split across the day
Cycle lengthReported in short courses of a few weeks, sometimes with breaks; not standardised

Commonly reported as intranasal dosing over short courses of a few weeks, sometimes with breaks; reported patterns vary and are not standardised. This is reported information, not advice.

Best used with / commonly stacked with

Combinations people report using together. Reported, not recommended, stacking can increase risks.

Semax

Reported frequently paired as a complementary nootropic for mood and focus

Noopept

Reported combined for added cognitive effects

Cerebrolysin

Reported discussed together within neuro-focused stacks

Safety notes

Selank is not approved for human use in Australia and its long-term safety in humans is not well characterised. Grey-market product purity and identity cannot be verified by consumers. Anyone with a health concern should consult a qualified healthcare professional rather than self-experiment.

References

  1. PubMed, Selank research literature
  2. PubMed, Selank anxiety studies